Thyroid Dysfunction in Diabetic Patients: A Clinical Study of 140 Cases and Its Impact on Glycemic Control and Metabolic Health

• SYED MAHMOOD-UL-HASSAN

  Assistant Professor of medicine , Medical Unit 01 , Services Hospital , Lahore

  Author

• MUHAMMAD IMRAN

  Consultant physician , Medical unit 2 , Services hospital , Lahore

  Author

• MUHAMMAD USMAN GHANI

  MBBS , FCPS Medicine Senior Registrar , Medical Unit 01 , Services Hospital lahore

  Author

Background: Thyroid dysfunction is a commonly observed complication in diabetic patients. Hypothyroidism and hyperthyroidism can adversely affect glycemic control, insulin resistance, and metabolic health. This study aims to evaluate the association of thyroid dysfunction with diabetes and its impact on various metabolic parameters in 140 diabetic patients.

Objective: To assess the prevalence of thyroid dysfunction in diabetic patients and its impact on glycemic control, insulin resistance, and lipid profile.

Methods: A cross-sectional study was conducted involving 140 diabetic patients (70 Type 1 and 70 Type 2). Thyroid function was evaluated using TSH, Free T4, and Free T3 levels. Glycemic control was assessed by HbA1c, insulin resistance by HOMA-IR, and lipid profile and BMI were also evaluated.

Results: Thyroid dysfunction was observed in 40% of the diabetic patients, with hypothyroidism being more prevalent in Type 1 diabetes and hyperthyroidism in Type 2 diabetes. Insulin resistance was significantly higher in those with thyroid dysfunction.

Conclusion: Thyroid dysfunction has a significant impact on diabetes management and metabolic health. Regular thyroid screening in diabetic patients is recommended for better control and management.

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