Frequency of In-Hospital Survival and Mortality in STEMI Patients Complicated by Cardiogenic Shock

• MUHAMMAD KASHIF ZAFAR

  Cardiology Department, Punjab institute of cardiology, Lahore

  Author

• SHAHZAD SHOUKAT

  Cardiology Department , Punjab institute of Cardiology , Lahore

  Author

Background: ST-segment elevation myocardial infarction (STEMI) complicated by cardiogenic shock (CS) is associated with high mortality rates. Primary percutaneous coronary intervention (PCI) is the recommended treatment, but outcomes remain suboptimal.

Objective: This study aimed to evaluate the clinical characteristics, procedural outcomes, and long-term survival of STEMI patients with CS undergoing primary PCI.

Methods: A retrospective cohort study was conducted on 160 STEMI patients with CS undergoing primary PCI at a tertiary care center from January 2018 to December 2024. Baseline demographics, clinical presentation, procedural details, and outcomes were collected. The primary endpoint was in-hospital mortality; secondary endpoints included major adverse cardiac events (MACE) and long-term survival.

Results: The mean age of the cohort was 58.2 ± 12.4 years, with 72% male. The in-hospital mortality rate was 34.4%, and MACE occurred in 22.5%. At a median follow-up of 36 months, the 3-year survival rate was 62.3%. Logistic regression analysis revealed that age >65 years, Killip class ≥3, and left ventricular ejection fraction <30% were independent predictors of poor outcomes.

Conclusion: Primary PCI in STEMI patients with CS is associated with significant mortality. Early identification of high-risk patients and timely intervention are crucial for improving outcomes.

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